Thursday, July 29, 2010


'Identical' cells? Not so much

"Genetically identical cells may be far more different than previously believed. Published this week in Science, researchers find striking variation in levels of gene expression among individual, genetically identical E. coli, seemingly the result of simple chance." They also find that "a single cell’s protein and mRNA copy numbers for any given gene are uncorrelated."

Read more @The Scientist. Full paper in Science:

Y. Taniguchi et al "Quantifying E. coli proteome and transcriptome with single-molecule sensitivity in single cells," Science, 329:533-8, 2010.

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