Thursday, February 28, 2013
Circular RNAs throw genetics for a loop
"Behold the latest curio in the cabinet of RNA oddities: naturally occurring circular RNA molecules that influence gene expression." News article @ Nature
Labels: genomics, RNA, transcription
Thursday, July 29, 2010
'Identical' cells? Not so much
"Genetically identical cells may be far more different than previously believed. Published this week in Science, researchers find striking variation in levels of gene expression among individual, genetically identical E. coli, seemingly the result of simple chance." They also find that "a single cell’s protein and mRNA copy numbers for any given gene are uncorrelated."
Read more @The Scientist. Full paper in Science:
Y. Taniguchi et al "Quantifying E. coli proteome and transcriptome with single-molecule sensitivity in single cells," Science, 329:533-8, 2010.
Read more @The Scientist. Full paper in Science:
Y. Taniguchi et al "Quantifying E. coli proteome and transcriptome with single-molecule sensitivity in single cells," Science, 329:533-8, 2010.
Labels: genomics, transcription
Wednesday, January 06, 2010
RNA Activation
"More findings confirm that small RNAs work in mysterious ways. Nearly 20 years after its discovery, RNA interference (RNAi) is part of biology’s orthodoxy. Small RNA molecules can disrupt gene expression by degrading messenger RNAs (mRNAs) on their way to becoming proteins, or otherwise interfering with translation. But the discovery that these same small RNA molecules might be able to do just the opposite—enhance gene expression—was somewhat heretical". Full article @ The Scientist.com.
Labels: RNA, transcription
