Tuesday, May 15, 2012
Rewiring the Networks for Cancer Treatment
Systems biology (from a complex system viepoint) starts producing important and practical results. "A systems-level analysis shows that, after their oncogenic signaling pathways are perturbed, tumor cells become more sensitive to DNA-damaging chemotherapy." Rewiring the Networks -- Foley 5 (224): ec135 -- Science Signaling. See also:
M. J. Lee, A. S. Ye, A. K. Gardino, A. M. Heijink, P. K. Sorger, G. MacBeath, M. B. Yaffe. [2012] Sequential application of anticancer drugs enhances cell death by rewiring apoptotic signaling networks. Cell 149, 780–794.
M. J. Lee, A. S. Ye, A. K. Gardino, A. M. Heijink, P. K. Sorger, G. MacBeath, M. B. Yaffe. [2012] Sequential application of anticancer drugs enhances cell death by rewiring apoptotic signaling networks. Cell 149, 780–794.
